韩国科学技术院（KAIST）与首尔大学盆唐医院的研究团队开发出一种可穿戴微流控眼药贴片，目标是在微重力环境下帮助宇航员自行滴眼药。研究发表于《传感器与执行器B：化学》期刊。NASA指出，微重力会使体液向头部移动，可能增加眼部压力并引发视力问题；而普通滴眼液依靠重力落入眼中，在失重环境下不易使用。
这款自助滴药微流控贴片由柔性材料制成，可贴在眼睛旁边，内部设有储液腔、化学反应腔和微通道。使用者按压贴片上的启动区域，预先浸湿的织物会释放少量水，使其与抗坏血酸（维生素C）和碳酸氢钠，也就是小苏打的主要成分，接触并产生二氧化碳。气体压力推动预装的药液沿微通道流向眼角，无需电池或外接泵。
反应腔与药液腔之间设有可透气、阻液的过滤层，让气体压力通过，同时隔开反应物和眼药，降低两者混合的风险。团队在不同重力方向下测试后发现，贴片都能较稳定地释放药液；在地面人体佩戴评估中，其给药表现与传统滴眼液方法相近。
研究目前仍是在地面实验中完成，尚未在真正的太空微重力环境中测试，因此不能视为已验证可在轨使用的医疗设备。研究团队表示，这种装置也可能帮助帕金森病患者等手部震颤或行动受限、难以准确自行滴眼药的人群；能否用于临床仍需进一步验证。
本文由 AI图鉴自动抓取并翻译，版权归原作者所有；如需查看原文请点下方链接。
The research team of the Korea Institute of Science and Technology (KAIST) and the University of Seoul Hospital in Pond has developed a micro-flow-controlled eye sticker designed to assist astronauts with their own eye drops in microgravity environments. Research is published in the journal Sensor and Executor B: Chemistry. According to NASA, microgravity allows body fluids to move to the head, which may increase eye pressure and cause visual problems, while ordinary droplets rely on gravity to fall into the eye and are not easily used in weightlessness.
The micro-flow control sticker, which is made of soft material, can be attached to the eye and has a liquid cavity, a chemical reaction cavity and a microchannel inside. By pressing the starting area on the tablet, pre-wetted fabric releases a small amount of water that exposes it to the main components of the anti-fatal acid (vitamin C) and sodium carbonate, i.e. small soda, and produces carbon dioxide. The gas pressure drives pre-positioned pharmacies to the eye angle along the microchannel without batteries or external pumps.
There is a filter layer between the reaction cavity and the liquid cavity of the drug, which allows gaseous pressure to pass while separating the reaction and eye medicine to reduce the risk of mixing. The team tested in different gravitational directions and found that the stickers were able to release the fluid more steadily; in the ground body wear assessment, the drug was given in a similar way to the traditional drop-out method.
The study is still being completed in ground-based experiments and has not yet been tested in a truly space microgravity environment and therefore cannot be considered to have been tested for on-orbit medical equipment. According to the research team, such devices may also assist people with hand shocks or movement restrictions, such as Parkinson patients, who have difficulty obtaining accurate self-observation medications; their use for clinical purposes remains to be further tested.
Auto-fetched and translated by AI Atlas. All rights belong to the original author.